Abstract: 【Objective】 The purpose of this study is to screen herbicides with good efficacy against broadleaf weeds in barley fields and provide a basis for safe and efficient application of herbicides in desert oasis ecological zones. 【Methods】 A randomized block design was conducted to this study and the number of weed plants and the fresh mass of above-ground parts in each treatment plot were investigated to evaluate the effectiveness of the test agents on broadleaf weeds and the safety of the barley plants in barley fields. 【Results】 50 d after herbicides application,20% florasulam- halauxifen-methyl WG 19.50 g/hm²,10% bipyrazone OD 37.50 g/hm²,200 g/L fluroxypyr EC 210.00 g/hm²,22% bipyrazone-fluroxypyr 165.00 g/hm²,50% MCPA-isooctyl-fluroxypyr-florasulam SC 450.00 g/hm²,87.5% 2,4-D isooctyl ester EC 577.50 g/hm²,25% bormoxynil octanoate EC 562.50 g/hm² and 75% tribenuron methyl WG 22.50 g/hm² all had great control effects of the quantity and fresh weight of weeds on Chenopodium glaucum with the range from 90.87% to 96.02% and on Fallopia convolvulus with the range from 94.15% to 98.08%. There was no significant difference between the treatment strains and fresh quality. 【Conclusion】 20% florasulam- halauxifen-methyl WG,10% bipyrazone OD,200 g/L fluroxypyr EC,22% bipyrazone-fluroxypyr OD,50% MCPA-isooctyl-fluroxypyr-florasulam SC,87.5% 2,4-D isooctyl ester EC,25% bormoxynil octanoate EC and 75% tribenuron methyl WG have the capability to control broadleaf weeds like Chenopodium glaucum and Polygonum capitatum in barley fields,and it is safe for barley growth and can be used in reasonable rotation in barley fields.