新疆焉耆县不同动物源大肠杆菌耐药性调查

doi:10.6048/j.issn.1001-4330.2017.12.019

新疆农业科学 ›› 2017, Vol. 54 ›› Issue (12): 2314-2319.DOI: 10.6048/j.issn.1001-4330.2017.12.019

新疆焉耆县不同动物源大肠杆菌耐药性调查

姚晓慧¹, 隆茂俊¹, 库尔班乃木·卡地尔², 王凯¹, 夏利宁¹

1.新疆农业大学动物医学学院,乌鲁木齐 830052;
2.新疆焉耆县畜牧兽医站,新疆焉耆 841100

收稿日期:2017-11-04 出版日期:2017-12-25 发布日期:2018-01-29
通信作者: 夏利宁(1975-),女,湖南宁乡人,教授,博士,硕士生导师,研究方向为兽医药理与毒理学,(E-mail)xln750530@163.com
作者简介:姚晓慧(1994-),女,甘肃人,硕士研究生,研究方向为兽医药理与毒理学,(E-mail)13209963303@163.com
基金资助:
国家自然科学基金项目“新疆联合基金项目”(U1503185)

Survey of Resistance of Escherichia coli from Different Animals to Antimicrobials in Yanqi, Xinjiang

YAO Xiao-hui¹, LONG Mao-jun¹, Kuerbannaimu Kadier², WANG Kai¹, XIA Li-ning¹

1.College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.
2. Animal Husbandry and Veterinary Station, Yanqi County, Yanqi Xinjiang 841100, China

Received:2017-11-04 Online:2017-12-25 Published:2018-01-29
Correspondence author: Xia Li-ning (1975- ), female, native place: Ningxiang, Hunan. Professor,Doctor, master Supervisor, research field: Veterinary Pharmacology and Toxicology, (E-mail)xln750530@163.com
Supported by:
National Natural Science Foundation of China - Xinjiang Joint Fund Project(U1503185)

摘要/Abstract

摘要： 【目的】调查新疆焉耆县不同动物粪源大肠杆菌对临床常用抗菌药物的耐药情况。【方法】从该县主要的规模化养殖场分别采集仔猪(日龄分别为40和60 d)、妊娠母猪、牛及羊的粪便。采用琼脂稀释法,对分离出的大肠杆菌进行最小抑菌浓度测定。【结果】猪粪源大肠杆菌对被检抗菌药物耐药严重程度依次为40日龄仔猪>60日龄仔猪>妊娠母猪粪源大肠杆菌;牛源大肠杆菌(除阿米卡星)和羊源大肠杆菌(除安普霉素)对其他被检抗菌药物均有不同程度的耐药。仔猪粪源大肠杆菌以6~8耐为主(40日龄:89.2%,74/83;60日龄:49.0%,49/100),妊娠母猪粪源大肠杆菌以2~4耐为主(63.3%,62/98),牛粪源大肠杆菌以1~2耐为主(58.0%,47/81),羊粪源大肠杆菌以0~2耐为主(80.2%,138/172)。【结论】新疆焉耆县主要的规模化养殖场不同动物粪源大肠杆菌对临床常用抗菌药物的耐药程度不同,但在养殖过程中应考虑耐药情况需合理使用抗菌药物。

关键词: 不同动物; 大肠杆菌; 最小抑菌浓度; 多药耐药

Abstract: 【Objective】 To investigate the resistance of Escherichia coli from different animals to commonly used antimicrobial agents in Yanqi County, Xinjiang. 【Method】Feces of piglets (aged 40 days and 60 days) were collected from the main farms in the county, and the feces of pregnant sows, cattle and sheep were collected, respectively. The minimum inhibitory concentration of Escherichia coli was determined by agar dilution method.【Result】The results showed that the resistance severity of fecal Escherichia coli from 40-day-old > fecal Escherichia coli from 60-day-old piglets > fecal Escherichia coli from pregnant sows. Escherichia coli from sheep and cattle had different degrees of resistance to detected antimicrobials. Escherichia coli from piglets was mainly resistant to 6-8 (40 days old: 89.2%, 74/83; 60 days old: 49.0%, 49/100), and pregnant sows was mainly resistant to 2-4 (63.3%, 62/98). Escherichia coli from cattle was mainly resistant to 1-2 (58.0%, 47/81) and sheep was mainly resistant to 0-2 (80.2%, 138/172).【Conclusion】Escherichia coli from different animals in the main farms had different degrees of resistance to the commonly used antibiotics in clinics in Yanqi County, Xinjiang, so in the breeding process, the rational use of antimicrobial agents should be taken into consideration in the case of bacterial resistance.

Key words: different animals; Escherichia coli ; minimal inhibitory concentration; multidrug resistance

中图分类号:

姚晓慧, 隆茂俊, 库尔班乃木·卡地尔, 王凯, 夏利宁. 新疆焉耆县不同动物源大肠杆菌耐药性调查[J]. 新疆农业科学, 2017, 54(12): 2314-2319.

YAO Xiao-hui, LONG Mao-jun, Kuerbannaimu Kadier, WANG Kai, XIA Li-ning. Survey of Resistance of Escherichia coli from Different Animals to Antimicrobials in Yanqi, Xinjiang[J]. Xinjiang Agricultural Sciences, 2017, 54(12): 2314-2319.

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新疆焉耆县不同动物源大肠杆菌耐药性调查

Survey of Resistance of Escherichia coli from Different Animals to Antimicrobials in Yanqi, Xinjiang

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