Abstract: Objective The study aims to screen out the herbicide with good control effect on the weeds in the field and to provide scientific basis for the safe and efficient application of the herbicide.MethodThe method of randomized block experiment was used in field trial and the amount of broadleaf weeds and grass weeds were investigated.ResultAfter 40 days, the result showed that the treatments of 10; monosulfuron WP with the dosage of 210 g a.i./hm2, 45; propazine-simetryn WP with the dosage of 1,181.25 g a.i./hm2 had better effect on grassy weeds and broadleaf weeds of summer millet, the control effect of plant number was above 86;, and the control effect of fresh weight was above 96;.48; dicamba AS with the dosage of 360 g a.i./hm2 had better effect on broadleaf weeds of summer millet, the control effect of plant number was 85.61;, and the control effect of fresh weight was 99.88;.ConclusionTwo dilution method was used for field spraying, 10; monosulfuron WP, 45; propazine-simetryn WP and 48; dicamba AS were recommended for application in summer millet field in Southern Xinjiang.