Abstract: 【Objective】 To screen the prevention and control agents suitable for Phthorimaea absoluta Meyrick in Kashgar based on the current situation of resistance of Phthorimaea absoluta Meyrick to a variety of insecticides in Kashgar, Xinjiang in the hope of providng a theoretical basis for the prevention and control of the disease in this area. 【Methods】 In this study, the leaf dip method was used to evaluate the insecticidal effect of four insecticides on the second instar larvae of Phthorimaea absoluta Meyrick miner, and the insecticidal effect was verified by field control experiment. 【Results】 The results of laboratory virulence test showed that the Phthorimaea absoluta Meyrick had a high sensitivity to the four tested insecticides, and its sensitivity was 0.5% matrine EC (0.046 mg/L)> 0.3% azadirachtin SL(0.485 mg/L)> 5% emamectin benzoate ME(0.681) mg/L> 20% acetamiprid SP(1.265 mg/L). The control effect of four insecticides on the larvae of Phthorimaea absoluta Meyrick beetle was remarkable, and the control effect of each agent could reach more than 90% after 14 days after treatment. 【Conclusion】 Four insecticides, namely acetamiprid SP, 5% emamectin benzoate ME, 0.5% matrine EC and 0.3% azadirachtin, can be used as effective agents for the control of Phthorimaea absoluta Meyrick in Kashgar Prefecture,Xinjiang.