Abstract: 【Objective】 To screen efficient seed coating agents and their optimal dosage based on the dominant pathogenic strain Fusarium Sporotrichioide (Fusarium verticillioides) corn stem rot disease in Xinjiang in the hope of providing guidance for scientific prevention and control of the disease in production. 【Methods】 The mycelial growth rate method was used in combination with field plot experiments and systematic evaluation of the indoor antibacterial effect and field actual control effect of five coating agents on Fusarium Sporotrichioide. 【Results】 The indoor toxicity test showed that the five tested seed coating agents had good antibacterial effects on the strain, with an EC₅₀ range of 0.193 mg/L to 44.142 mg/L. In terms of field control effectiveness, 35 grams/liter of Loxomyces cerevisiae · Jingjia frost FS 175 mL/100kg seeds was the highest, accounting for 84.96%. The next in order was 18% thiacloprid · chlorpyrifos · chlorpyrifos FS 250 mL/100kg seeds, 30% imidacloprid · chlorpyrifos FS 750 mL/100kg seeds, 35 g/L Loxobacterium · chlorpyrifos FS 150 mL/100kg seeds, and 18% thiacloprid · chlorpyrifos · chlorpyrifos FS 200mL/100kg seeds, all with control effects ranging from 74.11% to 84.72%. 【Conclusion】 The seed coating agent and its recommended application amount for the field control of Fusarium oxysporum stem rot disease in Xinjiang corn is 35 g/L Loxomyces · Fenpropafenone FS (125-175) mL/100kg seeds, 18% Thiazolin · Fenpropafenone FS (150-250) mL/100kg seeds, 4% Fenpropafenone FS (120-150) mL/100kg seeds, and 30% Fenpropafenone · Fenpropafenone FS (600-750) mL/100kg seeds.