Abstract: 【Objective】 This study was conducted to clarify the current situation of wheat diseases, pests and grasses in Xinjiang, and put forward scientific and reasonable comprehensive prevention and control strategies. 【Methods】 The types, damage distribution and drug use of wheat pests in the main wheat producing areas of Xinjiang were investigated and recorded by means of questionnaire survey, field visit, field investigation and data collection, and the prevention and control countermeasures were analyzed. 【Results】 There were many kinds of wheat pests in Xinjiang, among which frequent major pests such as wheat stripe rust, powdery mildew and aphids showed a tendency of multiple recurrence; minor diseases and pests such as wheat root rot, stem rot, nematode disease and dermatithrips tended to evolve into explosive major pests; resistance of dominant weeds in wheat fields tended to increase sharply. At present, chemical control was the main method for wheat pest control in Xinjiang. The frequency of administration was 1~2 times, and the control effect was relatively good. However, it is urgent to strengthen the research on the disaster regularity of wheat pest outbreak, the research and development of monitoring technology and pesticide products, the application of drug application equipment and the application of control and control. 【Conclusion】 We will increase the investment of innovation research and development in wheat plant protection technology and the construction of innovation system and mechanism, strengthen the basic theoretical research of wheat plant protection, innovate green pest control and intelligent monitoring technologies, improve the wheat plant protection service system, and provide technical support for the comprehensive control of wheat pests in Xinjiang.