Abstract: 【Objective】 The actual improvement effect of synergist, microelement fertilizer, stem and leaf spray and seed coating agent coating on the control effect of corn stem rot was determined, in order to establish a set of efficient control technology of corn stem rot in Xinjiang. 【Methods】 Based on the scientific use of seed coating drugs, field trials were conducted to determine the field efficacy of its synergistic application with two synergists, two micro fertilizers, and five stem and leaf fungicides against corn stem rot disease. 【Results】 When using 200 mL of 18% Thiamethasone, Chloramphenicol, and Vitamin A FS and 150 mL of 5 g/L Chloramphenicol, Chloramphenicol, and Vitamin A Cream FS to coat every 100 kg of seeds, adding a 4000 fold dilution of Jijian solution/3000 fold dilution of Daxiao solution can increase the efficacy by 5.49%-5.84% and 5.03%-6.54%, respectively, compared to not adding a synergist; The control effect of using seed coating agent+agricultural zinc sulfate 5 mL/150 mL or soluble silicon 5mL/150 mL base fertilizer treatment increased by 2.05%-4.86% or 2.60%-2.96% compared to using seed coating agent alone; The control effect of the combined treatment of seed coating agent+stem and leaf spray was also improved to a certain extent compared with that of seed coating agent alone, increased by 1.06%-6.53% respectively. 【Conclusion】 On the basis of seed coating agent seed dressing control, combined with the addition of 4,000 times of Jijian solution/3,000 times of Daxiao solution, or the use of zinc sulfate as the base fertilizer, or the use of 10% difenoconazole 2,000 times of solution for stem and leaf spray treatment, can be used as a supporting method to improve the field control effect of corn stalk rot in Xinjiang.