Abstract: 【Objective】 The screening of mixed types and application amounts of high-efficiency insecticides for maize in the Ili River Valley, and the research on the matching technology of reducing and increasing efficiency were carried out to provide guidance for the coordinated and efficient control of major pests of maize in Xinjiang and cost-saving and efficiency-increasing. 【Methods】 By using plant protection drones to spray pesticides with different insecticidal mechanisms, and at the same time with synergistic additives to reduce the application of the mixed combination of pesticides, the actual control effects on Ostrinia furnacalis, Monolepta hieroglyphica and Helicoverpa armigera were compared and analyzed. 【Results】 The results showed that the control effects of different compound insecticides on Ostrinia furnacalis, Monolepta hieroglyphica and Helicoverpa armigera were different.The control effect of 30% chlorantraniliprole + 9.8% emamectin benzoate·lufenuron on the main pests of maize was better than that of 30% chlorantraniliprole + 22% thiamethoxam·high chlorine fluoride.The best pesticide and dosage for the control of pests by drone application were as follows : 30 % chlorantraniliprole SC 7.5 mL/667m² + 9.8% emamectin benzoate·lufenuron (Sipurui) SC 18.75mL/667m² + 10 mL/667m².After 28 days of treatment, the control effects on Ostrinia furnacalis, Monolepta hieroglyphica and Helicoverpa armigera were the highest, and the control effects were 91.68%, 93.44% and 91.22%, respectively.Under the same formula of compound agents, the addition of flight prevention additives can reduce the dosage and increase the control effect. 【Conclusion】 Treatment 5 is the best.Pesticide application at the big trumpet stage of corn can prevent a variety of corn pests.In addition, adding an appropriate amount of anti-aircraft additives in the process of anti-aircraft can achieve a better effect of reducing pesticide and increasing application.