Abstract: 【Objective】 To study the degree of functional coupling and coordination of the "three living spaces" in the four southern Xinjiang prefectures. 【Methods】 Eleven years of Xinjiang Statistical Yearbook and China County Statistical Yearbook (2001-2021 panel data) were collected as the main data sources and the evaluation index system of the function of the "three living spaces" in the four southern Xinjiang prefectures was constructed by using relevant indicators.On this basis, the Tobit model was then used to detect the influencing factors. 【Results】 Aksu region has the best coupling coordination of the "three living spaces “functions, with an average coupling coordination value of 0.532, which was barely coordinated, while the remaining three prefectures were Kashgar, Hotan and Kizilsu in descending order of coupling coordination. 【Conclusion】 The overall coupling coordination degree of the "production-living-ecological space" in the four southern prefectures is at a low level, and the coupling coordination level is on the verge of disorder, among which the total fixed asset investment and total social consumption goods per capita are positively influenced at the level of 1%, which has a certain influence on the "three living spaces" in the four southern regions.