Abstract: 【Objective】 To determine the enrichment and distribution of five heavy metals in melon plants. 【Methods】 From June 26 to July 25, ICP-MS was used to determine Cu, Cd, As, Cd, Cr and Ni analyzed the distribution of five heavy metals in different growth stages. Furthermore, through the percentage of the enrichment coefficient of five heavy metals in each plant, the change and the correlation of five heavy metals in melon plants were explored. 【Results】 From June 26 to July 25, The enrichment assignments of Cr, Ni and As were distributed by root> leaf> stem> stem> fruit; In contrast, the enrichment of Cu from 26 June to 25 and Cd from 26 June to July 16 was assigned leaf> root> stem> fruit; with the extension of time, the proportion of Cr, As, and Cd increased first and then decreased and the proportion of Ni and Cu showed a downwards trend. When the enrichment allocation of fruit Cr, As, Cu and Ni increased, the enrichment allocation of these four heavy metals in the roots tended to decrease, while the enrichment allocation of Cr, As and Ni in the leaves increased. Meanwhile, there was a decreasing trend in the Cd and Cu. 【Conclusion】 The above results show that the distribution, enrichment proportion of the five kinds of heavy metals in melon plants and the related sites is different according to the different types of heavy metals.