Abstract: 【Objective】 To study the effects of two cultivation modes on the cluster micro-environment and fruit development of Marselan grape in Turpan-Hami Basin in the hope of providing reference for the selection of wine grape cultivation modes in production areas. 【Methods】 The research was carried out in Marselan grape with L-MVSP(Fruit setting height 40 cm,the treatment group) and H-MVSP(Fruit setting height 80 cm,the control group) in Turpan-Hami Basin,the changes of micro-environment index on the cluster region and berry development index during fruit growth period,fruit quality and anthocyanin composition during harvest under two cultivation modes were compared and analyzed under two cultivation modes. 【Results】 The daily maximum temperature and daily average temperature of the cluster region micro-environment were lower for L-MVSP than for H-MVSP,with 1.66 and 2.21℃ respectively,the sum of temperature difference exceeding 35℃ and the time of temperature exceeding 35℃ were decreased for L-MVSP than for H-MVSP,with 39.25℃ and 40.12 h respectively; The daily maximum humidity,daily minimum humidity and daily average humidity were 2.89%,1.70% and 2.64% higher,respectively for L-MVSP than for H-MVSP,the daily average low humidity duration was 11.56 h lower for L-MVSP than for H-MVSP; The leaf canopy transmission radiation,soil reflection radiation and total radiation were 36.94%,50.38% and 44.91% lower,respectively for L-MVSP than for H-MVSP. The L-MVSP was more benefit for fruit development than H-MVSP,tartaric acid,malic acid and ascorbic acid were higher for L-MVSP than H-MVSP at veraison,grape in L-MVSP had a higher cluster quality and fruit grain quality,increased by 38.74% and 25.61% respectively,the wilting rate decreased by 14.20%,the soluble solids decreased by 2.67 ° Brix,the total acid mass concentration increased by 0.83 g/L,and the total flavanol content and total anthocyanin content increased by 23.83% and 5.80%,respectively. However,the proportion of 3',5'-hydroxy substituted anthocyanins,the proportion of methylation modification of anthocyanins and the proportion of total modification of anthocyanins were decreased in L-MVSP. 【Conclusion】 The L-MVSP of wine grape Marselan can improve the cluster region micro-environment and improve the berry quality in Turpan-Hami Basin.