Abstract: 【Objective】 To study the effects of six copper preparations on the main vine length, stem diameter, maximum functional leaf area, maximum functional leaf node position, relative chlorophyll content SPAD value, single melon weight, central sugar content, diseased leaf rate and copper damage index of melon. By comparing the influence of the six copper preparations on melon copper damage, the best agent among the six copper preparations was selected to provide a reference for the safe use of copper preparations in muskmelon production. 【Methods】 Through field experiments, six kinds of copper preparations with different concentrations were sprayed on the leaf surface at the melon seedling stage, the growth indicators such as the length of the main vine and the maximum functional leaf area of stem diameter were measured, and the diseased leaves were counted at the peak of copper damage in melon rate and copper damage index. 【Results】 The six kinds of copper preparations had little effect on various growth indexes and single melon weight when diluted 1,000 times. Among them, 46% could kill 3,000 WP. The rate of diseased leaves and copper damage index were 9% and 14.83; except for B₄ and C₄ treatments, the 6 kinds of copper preparations with different dilution times had no significant effect on the sugar content in the center of melon; When the six copper preparations were diluted 500 times, the copper damage of melon plants was aggravated. 【Conclusion】 Among the six copper preparations, 99% copper acetate was very easy to cause copper damage to melon plants, 99% copper sulfate was the second, and 33.5% quinoline copper suspending agent 30% copper succinate WP, 23% copper rosinate EC and 46% that can kill three thousand water dispersible granules are relatively safe for melon.