Abstract: 【Objective】 To understand the effects of amine fresh and methylperidium compound on the growth and development of cotton, and to clarify the effect of amine fresh and meperamide compound on cotton yield increase of different foliar fertilizers, 【Methods】 The experiment was carried out in Dafeng Town, Hutubi County in 2021, using Xinluzao 82, mainly amine fresh and methyl, respectively, compounded acetylamine, auxiliary, borozin fertilizer, potassium scalemate, silicon fertilizer; Single administration of acetylamine was taken the control. In this experiment, the effects of different treatments on the agronomic traits, dry matter accumulation and yield quality of cotton were analyzed. 【Results】 The results showed that different treatments showed different degrees of regulation of plant height, among which the treatment of amine fresh meperidium + additive + boron zinc fertilizer had a strong ability to inhibit plant height. In terms of dry matter accumulation, the amount of drifting dry matter accumulated by foliar sprays of amine fresh, meperamide + additive + potassium phosphite was the largest in all treatments, reaching 45.37 g/plant, and the total dry matter weight was the highest, reaching 83.71 g/plant; In terms of yield, the number of bolls per plant sprayed with amine fresh, meperidium + additive + boron zinc fertilizer reached a maximum of 6.78 per plant, and the maximum weight of a single bell was 6.41 g, and the yield of seed cotton harvested by spraying amine fresh o meperidium + additive + potassium phosphite was the highest, which was 10.42% higher than that of the control. 【Conclusion】 Therefore, the combination of amine fresh o meperidium + auxiliaries + potassium phosphite has the best yield enhancement effect.