Abstract: 【Objective】 Effects of cadmium stress on juvenile hormone and molting hormone titers in Spodoptera exigua. The effect of heavy metal on growth and development of insects from the perspective of insect physiology in the hope of providing a basis for ecological risk assessment and pollution control of heavy metals. 【Methods】 In this study, artificial diet containing four concentrations of Cd²⁺ (0, 0.2,3.2, 51.2 mg/kg) were used to feed the newly hatched larvae of Spodoptera exigua until pupation.Then the titers of juvenile hormone and molting hormone at different growth stages (3rd instar, 5th instar, female adult and male adult) of S.exigua were determined. 【Results】 The results of this experiment showed that the titers of juvenile hormone and molting hormone in larvae increased under low concentration cadmium stress (0.2 mg/kg).With the increase of cadmium concentration, the titers of juvenile hormone and molting hormone gradually decreased.The titers of juvenile-preserving hormone and molting hormone increased in Spodoptera exigua under cadmium stress, and the titers of juvenile-preserving hormone and molting hormone did not change significantly with the increase of cadmium concentration. 【Conclusion】 The results indicate that cadmium stress has significant effects on the titers of two hormones in S.exigua.