Abstract: 【Objective】 This project aims to study the effects of spraying different types of foliar fertilizers on grain yield and quality of winter wheat in the hope of providing references for leaf formula fertilization and high-efficiency production of winter wheat. 【Methods】 The wheat cultivars Xindong No.20 was used as testing material.Under field conditions, four treatments including Duntianbao, KH₂PO₄+ CO(NH₂)₂, Photosynthetic bacteria (PSB) fertilizer, CK (spraying water) were set during grain filling stage.The grain yield, component factors and grain quality of winter wheat were determined. 【Results】 Compared with CK, all the three kinds of foliar fertilizers could significantly increase the grain yield of wheat, and the yield-increasing effects of foliar fertilizer on the wheat was Duntianbao > KH₂PO₄+ CO(NH₂)₂ > PSB fertilizer, and their growth rates reached by 7.46%, 6.08% and 5.15%, respectively.Through the analysis of yield components, it was found that the three foliar fertilizer treatments could increase the grain yield of wheat mainly by increasing the 1,000-grain weight and kernels weight per spike.Among the three foliar fertilizers, the performance of PSB fertilizer in improving the grain quality of wheat was slightly better than those of KH₂PO₄+CO(NH₂)₂ and Duntianbao.Compared with CK, three kinds of foliar fertilizer significantly increased wheat grain protein content and stabilization time, in addition, PSB fertilizer significantly increased wheat grain wet gluten content. 【Conclusion】 Therefore, proper application of foliar fertilizer in grain filling stage is an effective technical measure for high quality and yield of winter wheat, among which, PSB fertilizer can significantly improve the grain yield and quality of wheat, so it can be used as an environment-friendly fertilizer for wheat production.