Abstract: 【Objective】 To grasp the spatial distribution and changes of cultivated soil nutrients in Tahe Basin. 【Methods】 Based on the sample point nutrient data (organic matter, total nitrogen, alkali-hydrolized nitrogen, available phosphorus and available potassium) in 2010 and 2018 in this region, statistical and geostatistical methods were used to combine with GIS technology to explore the spatiotemporal variability of ploughed soil. 【Results】 From 2010 to 2018, the indicators of topsoil were in moderate intensity variation, among which the highest coefficient of variation was 85.79% of available phosphorus in 2018.According to the standardized Z value, the standardized Z value of all indicators in 2018 was lower than that in 2010, indicating that the spatial autocorrelation of the following indicators weakened in recent years.The nutrient index content was low in all four weeks and high in the middle.Under different soil types, the nutrient content of tidal soil increased the least, while under the other two types of soil there was a significant increase.Under different irrigation methods, the nutrient content of both drip and diffuse irrigation increased, but the increase of nutrient content under diffuse irrigation was lower than that under drip irrigation. 【Conclusion】 Human activities, such as straw mulching, fertilization and rotation rest, are the main factors affecting the spatiotemporal changes of soil nutrients.