Abstract: 【Objective】 To explore the spatiotemporal expression and stress response properties of HcSCL13 genes in Halophytes caspica (Bieb.) C. A. Mey. 【Method】 The full-length promoter (2,230 bp) and truncated sequence of the gene were fused to the GUS reporter to detect the GUS histochemical staining and enzyme vitality of genetically transformed plants. 【Results】 Both aerial and underground parts of PHcSCL13.GUS homozyous Arabidopsis showed strong GUS staining at the stage of seed germination and seedling. With the development of transgenic PHcSCL13.GUS plant, the promoter activity displayed spatial and temporal patterns. Meanwhile, the promoter of HcSCL13 gene was responsive to light, salt and mechanical damage by GUS staining and activity analysis. After transient transformation of different length promoter fragments into the tobacco, the results of GUS activity suggested that the region for -1,124-1,450 bp upstream of the HcSCL13 promoter was responsible for its activity, while -1,730-2,230 bp upstream of the promoter was the salt response region. 【Conclusion】 The above finding shows that HcSCL13 genes in Halophytes caspica (Bieb.) C. A. Mey. express space-time specificity and response properties to light, salt and mechanical damage, which lays the foundation in molecular mechanism.