Abstract: 【Objective】 To study the effects of vibration of different intensity on mechanical damage and storage quality of Hami melon during transportation with the view of providing some theoretical basis for finding ways to reduce the influence of transportation vibration on storage quality of the fruit. 【Method】 In this study, the vibration conditions of Hami melon during transportation were simulated and the packaging was arranged as half basket packing and whole basket packing.After that, the mechanical damage of cantaloupe was analyzed after 2 h, 4 h and 6 h vibration treatment.The weight loss, soluble solids, hardness, pectin content and related hydrolases were determined and analyzed. 【Result】 On the 12 d after harvesting, the commodity rate of the half-basket treated for 6 h (T₃) dropped to the lowest, at 70.00%, the rot index was 0.96, and its hardness was reduced by 12.64% compared with the control; on the 9 d of harvesting, the half-basket was vibrated for 6h The weight loss rate of the treatment (T₃) increased the most compared with the control, with an increase of 8.1%. The soluble solid content of each treated cantaloupe ranged from 13.91% to 16.52%, and the overall change trend was small. In addition, the average number of damages per fruit was the highest in the half-frame vibration treatment (T₃), reaching 4.65g, and the damage area was 4.34% at most. Vibration also induced a large accumulation of pectin esterase (PE) and polygalacturonase (PG), especially on the 9 d of harvesting, the PE and PG of the half-basket vibrating for 6h treatment (T₃) increased respectively relative to the control. 224.13% and 361.29%, the content of protopectin and total pectin, the main components of the cell wall, decreased rapidly. In addition, the research results also believe that compared with the half-basket packaging method, the full-basket packaging method will reduce the mechanical damage of fruits during storage and transportation. 【Conclusion】 Transportation vibration not only causes mechanical damage of Hami melon, but also causes rapid softening and reduces storage quality.In addition, compared with half-basket treatment, full-basket packaging can reduce the mechanical damage of the melon caused by transportation vibration and improve the commodity value.