Abstract: 【Objective】 To study the effect of microclimate on the quality of grape fruit under the control of mist, and to determine the way of mist control with high quality and high yield, so as to provide theoretical basis and data support for promoting water-saving and quality improvement of grape. 【Methods】 the basis of conventional drip irrigation, a micro spray mist control irrigation technology was formed by superposing with micro spray.Through monitoring the changes of temperature, humidity, fruit quality and other indicators in vineyard under the micro spray mist control, the response relationship between micro climate factors and grape fruit quality under the mist control was clarified. 【Results】 with CK treatment, the mean temperature in daytime was 1.5-3.0℃ lower, the mean temperature at night was 1.3-2.1℃ lower, the mean temperature difference was 0.1-1.6℃ lower, the mean temperature was 1.5-2.5℃ lower, the mean humidity in daytime was 5.7%-7.6%, the mean humidity at night was 4.7%-7.0%, and the mean humidity was 5.0%-7.0%.In terms of fruit quality, soluble solids content of WP₁, WP₂, WP₃ and CK were 21.5%, 21.1%, 19.5% and 19.1% respectively, total sugar content was 19.1%, 18.2%, 17.9% and 17.5% respectively, total acid content was 4.0, 5.1, 5.9 and 6.4 g/L respectively, VC content was 2.8, 2.5, 2.5 and 2.1 μg/g respectively.Meanwhile, the fruit 0.26 higher than CK treatment In the process of grape fruit growth and development, the average humidity at night the key microclimate factor that the greatest impact.According to the correlation and regression model, when the average humidity at night 46.2%-51.1%, it beneficial to improve the quality of grape fruit. 【Conclusion】 the critical period of grape fruit growth, using the technology of mist control under the shelf and spraying water for 1 hour every day is beneficial to improve the quality of grape fruit, and the average humidity at night can be used to analyze and predict the growth and quality changes of grape fruit in this area.