Abstract: 【Objective】 To explore effects of the organic fertilizer combined with chemical fertilizer on the cotton growth character and yield. 【Method】 The effects of the partial substitution for chemiacal fertilizer with organic manure (20%、40% or 100%) on the cotton growth character and yield was ananlyzed by field experiment,with no fertilizer (CK) and inorganic fertilizer (CF) as the control. 【Results】 The change law of leaf number,plant height,stem diameter,SPAD value and yield at different growing periods of cotton is consistent:There was no significant difference between T₁ and T₅; The test of significance of difference between T₁ and T₂, T₃, T₄ was significant; The test of significance of difference between T₅ and T₂, T₃, T₄ was significant;Compared with CF, the treatments of reducing 20%、40% chemical fertilizer with organic manure could significantly promote cotton growth and increase cotton yield. The cotton yield of T₃ and T₄ was 27.70% and 21.75% higher than that of non-fertilization treatmemnt (CK) respectly. 【Conclusion】 Organic fertilizer combined with chemical fertilizer can reduce chemical fertilizer and increase cotton yield.