Abstract: 【 Objective 】 To establish a method for simultaneous determination of four flavonoids (proanthocyanidins, rutin, naringin dihydrochalcone and quercetin) in the sarcocarp of Xinjiang wild apricot by high performance liquid chromatography.【 Method 】 Four flavonoids from Xinjiang wild apricot sarcocarp were separated by Hubble C18 (4.6 mm ×250 mm, 5 m) column, mobile phase A (methanol)∶ B (0.5% phosphoric acid solution) = 45∶55, elution at a flow rate of 1.0 mL/min. The method was validated by instrument precision, stability, repeatability and recovery.【 Result 】 The chromatographic peaks of proanthocyanidin, rutin and quercetin were well separated within 20 minutes. The linear range was 0.52-56 g/mL (r = 0.999,8-1). The recovery was 92.13%-96.70% and RSD was 0.89%-1.96%. The content of proanthocyanidins, rutin and quercetin were 7.325 mg/kg, 0.630 mg/kg and 0.009,58 mg/kg respectively. Naringin dihydrochalcone was not detected under this condition.【 Conclusion 】 The method is simple, rapid, accurate, stable and reproducible. It is suitable for the separation and determination of three flavonoids in Xinjiang wild apricot flesh.