Abstract: 【Objective】 The purpose of this study is to explore the effects of Uniconazole treatment with different concentrations on the branch growth and fruit quality of Korla Fragrant Pear in the hope of providing theoretical basis for the fruit cultivation. 【Method】 On the 25th day after anthesis, Uniconazole with concentration of 50, 150, 250, 350, 450 mg/L was sprayed on the leaves of the new shoots of Korla Xiangli Pear. The growth indexes such as the length and coarseness of the new shoots were measured regularly, and the fruit quality of each treatment was measured after the fruit matured. 【Results】 Uniconazole treatment effectively inhibited the increase of shoot length, internode length, leaf area and chlorophyll value of Korla Fragrant Pear. With the increase of treatment concentrations, the inhibition effect was more obvious, and effectively promoted the increase of shoot diameter. The effect of 150-450 mg/L Uniconazole was obvious. After treatment with Uniconazole, the weight of single fruit, soluble solids, VC content and total soluble sugar of Korla Fragrant Pear were increased to some extents; Meanwhile, with the increase of treatment concentrations, the ratio of stone cells to rough fruits was also increased, and the effect of 450 mg/L Uniconazole was the most significant. 【Conclusion】 Spraying 250-350 mg/L of Uniconazole on the leaves during the rapid growth period of the new shoots of Korla Fragrant Pear can effectively inhibit the growth of the new shoots, but has no obvious effect on the fruit quality. It can be applied to the regulation of the growth and development of Korla Fragrant Pear.