Abstract: 【Objective】 The research aims to present the feasible method of identifying the resistance of Cucumis melo L. cultured in polythene bags to Orobanche aegyptiaca in the hope of providing technical support for the breeding of varieties resistant to O. aegyptiaca. 【Methods】The study hydroponically cultured different varieties of C. melo L. in polythene bags to investigate influences of root exudates of various varieties on the induction activity for seed germination and parasitism of O. aegyptiaca, so as to assess resistances of various varieties. 【Results】 For the nine varieties of C. melo L. inoculated with O. aegyptiaca through hydroponic culture in polythene bags, their root exudates stimulated seed germination of O. aegyptiaca, while they had significant differences in terms of the number of shoot elongation. Then, the number of shoot elongation was taken to assess the resistances of the nine varieties of C. melo L. to O. aegyptiaca. The results indicated that test varieties exhibited differences with regard to the resistances to parasitism of O. aegyptiaca, and varieties k2-2, k2-7, and CEZ were superior to others in terms of the resistance. 【Conclusions】Identification results for resistances of the nine varieties of C. melo L. to O. aegyptiaca using hydroponic culture in polythene bags verified that the culture method is an effective indoor approach for identifying resistance of C. melo L. to O. aegyptiaca.