Abstract: 【Objective】 The purpose of this study is to investigate the changes of feed intake, daily gain, slaughter rate, organ development and blood biochemical indexes of Bashibai sheep with corn straw and wheat straw as neutral detergent fibers in diet to explore the effects of NDF from different straw sources on performance and blood biochemical parameters of Bashibai sheep. 【Method】 Twenty sheep with the body weight at (21.76±4.86) kg were selected and divided into two groups randomly, which were sorted into groupⅠ (diet with corn stalk as fiber source) and group Ⅱ ( Feeding wheat straw as a fiber source diet) respectively, pre-test period was 10 days, test period was 60 days. 【Result】 The results showed that there was no significant difference in the average daily gain, dry matter intake, ratio from feed VS weight, slaughter rate and stomach weight between the two groups (P>0.05). The liver and lung weights of groupⅠ were significantly higher than those of group Ⅱ (P<0.05). There was no significant difference in the contents of serum globulin, lactate dehydrogenase, aspartate aminotransferase and calcium and phosphorus between group Ⅰ and Ⅱ (P>0.05).The content of serum albumin, white ball ratio and triglyceride in groupⅠ were significantly higher than those in Group Ⅱ (P<0.05). 【Conclusion】 There is no significant effect on the growth performance and slaughtering performance of Bashibai sheep fed with the two kinds of straw derived NDF diets, but the diets derived from corn stalks has a great effect on the immunity of liver and lung organs. The diet with wheat straw as the source of NDF may be more conducive to the digestion and absorption of fat.