Abstract: [Objective] This study aims to research the effects of salinity-alkalinity stress on the seed germinations of Xinjiang Hami melon and screen out the most salt-tolerant varieties for the layout in Xinjiang.[Method]This experiment set five salinity-alkalinity stress,which were respectively 0(CK),25,50,75 and 100 mmol/L;The seeds of Hami melon were treated under salinity-alkalinity stress and the seeds germination rate,germination potential,germination index,vitality index were measured.[Result]With the increase of salinity stress concentration,the seed germinations parameters of Hami melon showed downtrend trend.The germination index,germination rate,germination index and vigor index were significantly different among varieties under saline alkali stress.The order of experimental Hami melon varieties from strong to weak was Xinmi 13 > Xinmi 28 > Hongmicui > Xinjiashi 2 > Xinmi 7 > 905-1 > Jinli2 > Nongmi 9 >Xinmi 43 > Lupi 9818 > Jiashigua > Xinmiza 11 >Xinmi31 > Xizhoumi 25 > Chunxiao 2 > Xinmi 24 > Lvbaoshi.[Conclusion]The seed germination rate,germination potential,germination index and root damage rate may serve as indicators to appraise salinity-alkalinity tolerance of Hami melon at germination stage.The salinity-alkalinity tolerance of Xinmi 13 is the strongest among the experimental Hami melon varieties,and Xinmi 28 takes the second place.The salinity-alkalinity tolerances of different varieties have significant differences.The Xinmi 13 and Xinmi 28 are the preferred varieties for the saline-alkali area.