Abstract: [Objective] This paper studies the relationship between the eco-agricultural combination pattern and the income of farmers and herdsmen in the four prefectures in Xinjiang inorder to provide scientific basis and reference for the development of ecological agriculture in four prefecurres in southern Xinjiang.[Method]On the basis of the relevant literature and field research, the empirical data of some townships and villages in the four prefectures (Aksu prefecture, Kashi prefecture, Kezilesu Kirgiz Autonomous Prefecture, and Hotan prefecture) were collected, compiled and summarized, and the linear regression model was applied to analyze the agricultural and animal husbandry industrialization management model in order to find out the main factors that were influencing the business model and animal husbandry industrialization.[Result]The income of urban and rural residents in the four prefectures of southern Xinjiang was relatively backward in the whole Xinjiang region, and the gap is obvious.The agricultural and herdsmen had low educational level and the top three agricultural and husbandry modes were: the mono-cropping, the single farming and agro animal husbandry ecotourism;Corporatization agriculture and animal husbandry mode was the most effective and the ecological farming management mode has the most significant impact on the income of farmers and herdsmen.[Conclusion]The more family property owned by the farmers and herdsmen, the more income;the more land resources invested by the farmers and herdsmen, the more the production efficiency and income increase;the industrial integration business model, the farming and animal husbandry tourism business model and the ecological cultivation and management model have significant impacts on the income of farmers and herdsmen, whose impact rate are 86.27;, 110.55; and 165.03;.